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Guerrero-Ospina, Juan Camilo
- Beneficial Effects of Passiflora edulis on Blood Pressure and Reduction of Oxidative Stress
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Authors
Juan Camilo Guerrero-Ospina
1,
Olga Alicia Nieto
1,
Melida del Pilar Zarate
1,
Nelsy Loango
1,
Beatriz Restrepo
1,
Patricia Landazuri
1
Affiliations
1 Universidad del Quindío. Armenia-Quindío, CO
1 Universidad del Quindío. Armenia-Quindío, CO
Source
Indian Journal of Science and Technology, Vol 11, No 43 (2018), Pagination: 1-8Abstract
Objective: To evaluated the effect of consuming P. edulis juice on blood pressure, activity of the Angiotensin-Converting Enzyme (ACE), and antioxidant capacity in hypertensive patients. Methods/Statistical Analysis: The study included two groups of patients, one received Passiflora. edulis (P. edulis) juice (2 g/day, in 2 ml) during four weeks and the other did not. To determine if differences exist among the results found for each group, parametric or non-parametric test were used. Findings: This intervention reduced systolic and diastolic pressure (142.4 to 125.2 mmHg and 79 to 76.1 mmHg, respectively) compared to the group not intervened (139.5 to 134.9 and 89.7 to 84.0 mmHg, respectively), (p < 0.05); in addition, higher anti oxidative capacity was found of the serum for the group intervened. Contrary to expectations, ACE increased in these patients. Application/Improvements: P. edulis juice diminished blood pressure and oxidative stress of patients who consumed it; however, the mechanisms through which both effects occur must be studied.References
- World Health Organization A global brief on Hypertension - World Health Day; 2013. p. 1–40.
- World Heart Foundation Cardiovascular disease risk factors Stress | World Heart Federation [Internet]. [cited 2017 May 30]. Available from: http://www.world-heart-federation.org/cardiovascular-health/cardiovascular-disease-risk-factors/stress/.
- Vardanyan R, and Hruby V. Synthesis of Best-Seller Drugs. 1st Edition; 2016. p. 329–57. https://doi.org/10.1016/B9780-12-411492-0.00022-5
- Charlton M, Thompson JP. Drugs acting on the heart: Antihypertensive drugs. Anaesthesia and Intensive Care Medicine. 2015; 16(5):227–31. https://doi.org/10.1016/j.mpaic.2015.02.007
- Kiriyama A, Honbo A, Nishimura A, Shibata N, Iga K. Pharmacokinetic-pharmacodynamic analyses of antihypertensive drugs, nifedipine and propranolol, in spontaneously hypertensive rats to investigate characteristics of effect and side effects. Regulatory Toxicology and Pharmacology. 2016; 76:21–9. https://doi.org/10.1016/j.yrtph.2016.01.003. PMid:26773344
- Leung AA, Daskalopoulou SS, Dasgupta K, McBrien K, Butalia S, Zarnke KB, Nerenberg K. Hypertension Canada’s 2017 guidelines for diagnosis, risk assessment, prevention, and treatment of hypertension in adults. Canadian Journal of Cardiology. 2017; 33(5):557–76. https://doi.org/10.1016/j.cjca.2017.03.005. PMid:28449828
- Poprac P, Jomova K, Simunkova M, Kollar V, Rhodes CJ, Valko M. Targeting free radicals in oxidative stress-related human diseases. Trends in Pharmacological Sciences. 2017; 38(7):592–607. https://doi.org/10.1016/j.tips.2017.04.005. PMid:28551354
- Popović Z, Matić R, Bojović S, Stefanović M, Vidaković V. Ethnobotany and herbal medicine in modern complementary and alternative medicine: An overview of publications in the field of I&C medicine 2001-2013. Journal Ethnopharmacology. 2016; 181:182–92. https://doi.org/10.1016/j.jep.2016.01.034. PMid:26807912
- Rawat P, Singh PK, Kumar V. Anti-hypertensive medicinal plants and their mode of action. Journal of Herbal Medicine. 2016; 6(3):107–18. https://doi.org/10.1016/j.hermed.2016.06.001
- Aguillón J, Maldonado ME, Loango Chamorro N, Arango SAV. Antioxidant and antiproliferative activity of ethanolic and aqueous extracts from leaves and fruits juice of Passiflora edulis. Perspectivas en Nutrición Humana. 2013; 15:13–25.
- Rojas J, Ronceros S, Palomino R, Salas M, Aza-ero R, Cruz HA. Efecto coadyuvante del extracto liofilizado de Passiflora edulis (maracuyá) en la reducción de la presión arterial en pacientes tratados con enalapril. Anales de la Facultad de Medicina. 2009; 70(2):103–8.https://doi.org/10.15381/anales.v70i2.957
- Lewis BJ, Herrlinger KA, Craig TA, Mehring-Franklin CE, DeFreitas Z, Hinojosa-Laborde C. Antihypertensive effect of passion fruit peel extract and its major bioactive components following acute supplementation in spontaneously hypertensive rats. Journal of Nutritional Biochemistry. 2013; 24(7):1359–66. https://doi.org/10.1016/j.jnutbio. 2012.11.003. PMid:23333089
- Restrepo RA, Loango N, Moncada MV, Landazuri P. Angiotensin-Converting Enzyme Inhibitory Activity of Passiflora edulis f. flavicarpa and Petroselinum crispum (Mill) Fuss. British Journal of Pharmaceutical Research. 2013; 3(4):776–85. https://doi.org/10.9734/BJPR/2013/3517
- Ronca Testoni S. Direct spectrophotometric assay for angiotensinconverting enzyme in serum. Clinical Chemistry. 1983; 29(6):1093–96. PMid:6303627
- Koracevic D, Koracevic G, Djordjevic V, Andrejevic S, Cosic V. Method for the measurement of antioxidant activity in human fluids. Journal of Clinical Pathology. 2001; 54(5):356–61. https://doi.org/10.1136/jcp.54.5.356. PMid:11328833. PMCid:PMC1731414
- Nabavi SF, Ebrahimzadeh MA, Nabavi SM, Eslami B. Antioxidant activity of flower, stem and leaf extracts of Ferula gummosa Boiss. Grasas y aceites. 2010; 61(3):244– 50.https://doi.org/10.3989/gya.110809
- Cheng HM, Park S, Huang Q, Hoshide S, Wang JG, Kario K. Vascular aging and hypertension: Implications for the clinical application of central blood pressure. International Journal of Cardiology. 2017; 230:209–13. https://doi.org/10.1016/j.ijcard.2016.12.170. PMid:28043670
- Butler MJ, Tanner RM, Muntner P, Shimbo D, Bress AP, Shallcross AJ. Adherence to antihypertensive medications and associations with blood pressure among African Americans with hypertension in the Jackson Heart Study (JHS). Journal of the American Society of Hypertension. 2017; 11(9):581–8. https://doi.org/10.1016/j.jash.2017.06.011. PMid:28895842. PMCid:PMC5603252
- Cordova FM, Zibadi S, Watson RR. Antioxidant and anti-inflammatory actions of passion fruit peel extract in modifying osteoarthritis, hypertension, and asthma. Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases; 2013. p. 633–9.
- Restrepo RA, Nieto OA, Aristizabal J, Landazuri P. Angiotensin-converting enzyme inhibition by Phthirusa Pyrifolia (Kunth) Eicher. World Journal of Pharmaceutical Sciences. 2014; 3(6):352–63.
- Landazuri P, Loango Chamorro N, Restrepo B. Medicinal plants used in the management hypertension. Journal of Analytical and Pharmaceutical Research. 2017; 5(2):5–7.
- Fyhrquist F, Forslund T, Tikkanen I, Gronhagen-Riska C. Induction of angiotensin I-converting enzyme in rat’s lung with captopril (SQ 14225). European Journal of Pharmacology. 1980; 67(4):473–5. https://doi.org/10.1016/0014-2999(80)90189-2
- Rojas J, Tomás G. Tamizaje Fitoquímico Y Actividad antioxidante in vitro De Passiflora Edulis Sims (Maracuyá). Revista Peruana de Química e Ingenieria Química. 2010; 13:23–9.
- Miroddi M, Calapai G, Navarra M, Minciullo PL, Gangemi S. Passiflora incarnata L.: Ethnopharmacology, clinical application, safety and evaluation of clinical trials. Journal of Ethnopharmacology. 2013; 150(3):791–804. https://doi.org/10.1016/j.jep.2013.09.047. PMid:24140586
- Saravanan S, Arunachalam K, Parimelazhagan T. Antioxidant, analgesic, anti-inflammatory and antipyretic effects of polyphenols from Passiflora subpeltata leaves - A promising species of Passiflora. Industrial Crops and Products. 2014; 54:272–80. https://doi.org/10.1016/j.indcrop.2014.01.038
- Choi S, Ryu KH, Park SH, Jun JY, Shin BC, Chung JH. Direct vascular actions of quercetin in aorta from renal hypertensive rats. Kidney Research and Clinical Practice. 2015; 351):15–21. https://doi.org/10.1016/j.krcp.2015.12.003. PMid:27069853. PMCid:PMC4811985